Life Extension, Circadian , 30 Liquid Vegetarian s

• UPC:737870230038.
• Product Dimensions:4.4 x 4.6 x 8.9 cm , 0.05 kg.

Description ----------- * Restoring the Body's Circadian Clocks * Dietary Supplement * 1 Daily * Non-GMO Our NEW Circadian formula combines melatonin with a unique citrus-peel extract to encourage y function of both central and peripheral circadian clocks, respectively. MicroActive Melatonin promotes optimal -wake cycles, and Nobiletin from young citrus peel supports y expression of genes that govern your peripheral circadian rhythms. Benefits at a Glance: * Promotes y whole-body circadian rhythms * Supports y -wake cycles * Helps maintain whole-body * Contains both melatonin and nobiletin citrus extract More facts about Circadian You’ve probably heard of circadian rhythms — they’re best-known for regulating your -wake cycles. In addition to the central circadian “clock” in your brain, the internal-time keeper that regulates , you also have peripheral circadian clocks in various organs that govern essential biological processes: heart rate, body temperature, hormone release, blood pressure, liver, kidney and pancreatic function, and more. But ageing, hectic modern lifestyles, and other factors can disrupt all of your circadian clocks — which can affect your . So we developed our Circadian formula to restore these natural rhythms: MicroActive Melatonin targets the central clock in your brain, while Nobiletin young citrus peel extract promotes y peripheral clocks, which control the rest of your body. Melatonin for y -wake cycling Peripheral circadian clocks exist in virtually every cell of your body and are organized hierarchically, with the central clock setting the pace by regulating y -wake cycles. Melatonin, known as the “ hormone,” is primarily synthesized at night in the brain by the pineal gland. Melatonin ensures that the central clock is properly regulating -wake cycles and aligning the peripheral clocks with the -wake cycles for whole-body . So the first step to y, whole-body circadian rhythms is to restore that central clock with Melatonin. Nobiletin for y peripheral circadian rhythms Nobiletin is a polymethoxylated flavone isolated from young citrus peel. It has been shown to exhibit neuroprotective and antioxidant properties as well as promote a y inflammatory response. Results from a recent pre-clinical study suggest that nobiletin may also help positively regulate peripheral circadian rhythms. It does so by directly activating a unique set of receptors widely expressed throughout the body, and known to play a key role in regulating circadian rhythms. Nobiletin promotes whole-body In another pre-clinical study, nobiletin regulates the expression of circadian genes which themselves control the expression of other genes with specific circadian functions in every cell. y expression of genes controlling circadian rhythms supports c, cognitive, liver, and kidney and also helps maintain y blood pressure, cholesterol, and triglyceride levels already within the normal range. Unique circadian formula By targeting both “central” and “peripheral” circadian clocks, our Circadian represents a novel, restorative approach to whole-body . Try Circadian today! Suggested Use ------------- Read the entire label and follow the directions carefully prior to use. Take one (1) daily, before bedtime, or as recommended by a care practitioner. Melatonin is naturally secreted from the pineal gland at night, and should be taken at night for optimal results. Other Ingredients ----------------- Medium chain triglycerides, vegetable (hydroxypropyl methylcellulose, chlorophyllin), microcrystalline cellulose, sodium alginate, carnauba wax, silica. Warnings -------- * Keep out of reach of children. * Do not exceed recommended dose. * Do not purchase if outer seal is broken or damaged. * When using tional supplements, please consult with your physician if you are undergoing for a medical condition or if you are pregnant or lactating. Caution: Do not consume alcohol, drive or operate machinery after taking this product. Store tightly closed in a cool, dry place. . Visit Manufacturer's Website ( http://www.lef.org/ ) Supplement Facts Serving Size: 1 Liquid Vegetarian A Per Serving %Daily Value Nobiletin [from young citrus fruit (peel)] 50 mg ** Melatonin (as MicroActive) 1.5 mg ** **Daily Value not established